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Renin Angiotensin Mechanism.

Testosterone: The Male Sex Hormone.

 

  • On onset of Puberty in the male, the hypothalamus starts producing “Gonadotropin Releasing Hormone (GnRH).

  • Under influence of GnRH the Pituitary Gland produces two hormones as,

    • Luteinizing Hormone (LH).

    • Follicle Stimulating Hormone (FSH).

  • LH stimulates the Leydig Cells (Interstitial cells) present in testes, which secretes the male sex hormone “Testosterone”.

  • FSH acts indirectly to stimulate the process of spermatogenesis.

  • The sertoli cells in seminiferous tubules of testes under influence of FSH and Testosterone start producing a protein called Androgen Binding Protein (ABP), testosterone remains attached with this protein and hence local concentration of testosterone increases.

  • Testosterone stimulates and maintains the process of spermatogenesis.

  • The spermatogenesis process is terminated by Inhibin a hormone secreted by Sertoli cells.

  • The testosterone is responsible for development of secondary sex characteristics in boys viz.

    • Facial and body hair growth.

    • Increased muscle mass.

    • Increase in height.

    • Broadening of shoulders.

    • Deepening of voice.

    • Adam's apple become prominent.

    • Enlargement of male sex organs.

  • The testosterone is also responsible for,

    • Spermatogenesis,

    • Maintaining the libido.

    • Maintaining the muscle mass and bone density.

    • Enhanced wound healing.

  • Low testosterone levels are called “Hypogonadism” and the disorder is characterized by,

    • A drop in sex drive

    • Poor erections

    • Low sperm count

    • Enlarged breasts.

Commonly asked question.

  1. Write a short note on male sex hormone “Testosterone”.
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