MCQs test on Manufacturing Defects of Tablets

MCQs test on Manufacturing Defects of Tablets

Test

 

1. Complete or partial loss of top and bottom crowns of a tablet from the main body is called….
   
   1.   Capping
   2.   Lamination
   3.   Mottling
   4.   Sticking
2. The separation of a tablet into two or more distinct layers is called -----
   
   1.   Capping
   2.   Lamination
   3.   Mottling
   4.   Sticking
3. Surface materials from a tablet that is sticking to the punch and being removed from the tablet surface is -------
   
   1.   Capping
   2.   Lamination
   3.   Mottling
   4.   Picking
4. Defect in which tablet material sticks to the walls of die is called----
   
   1.   Sticking
   2.   Mottling
   3.   Picking
   4.   Capping
5. Defect in which there is an unequal distribution of colors on a tablet is called as ------.
   1.   Orange peel effect.
   2.   Lamination
   3.   Mottling
   4.   Sticking
6. Which of the following is the solution for “Capping”
   1.   Pre-compression
   2.   Reducing the final compression rate
   3.   Using flat punches
   4.   All of the above.
7. One of the following is not the cause of the weight variation in tablets,
   1.   Granule size & size distribution
   2.   Poor Flow
   3.   Punch Variation
   4.   High concentration of binder
8. Hardness of tablets depends on the “weight of materials” and “space between upper and lower punch at the moment of compression”.
   
   1.   True
   2.   False
9. Defect in tablet manufacturing characterized by “deformed edges” is called as…
   1.   Picking
   2.   Whiskering
   3.   Sticking
   4.   Orange peel effect.
10. One of the major cause of “whiskering” is use of,
    
    1.   Concave punches
    2.   Convex punches
    3.   Biconvex punches
    4.   Flat punches
11. Bumping and surface of the applied film coating is extremely rough, the defect is called
    
    
    1.   Mottling
    2.   Whiskering
    3.   Orange peel effect
    4.   None of the above
12. Orange peel effect can be prevented by;
    1.   Thinning of the polymer solution.
    2.   Addition of additional solvents
    3.   Reducing spray rate and high pressure
    4.   All of the above.
13. One of the following is cause of Orange peel effect;
    1.   Inadequate spraying or spreading of the coating solution.
    2.   High compression force.
    3.   High spray rate and high pressure.
    4.   A and C.
14. The defect in tablet manufacturing where “Tablets become stuck together” is called as,
    1.   Mottling
    2.   Whiskering
    3.   Twinning
    4.   Orange peeling
15. Following can cause “Twinning” in tablets
    1.   Flat surface.
    2.   Excessive sticky coating material.
    3.   Improper drying
    4.   All of the above.
16. A tablet coating problem that causes breaking lines within logo and making it less visible is called,
    
    1.   Double impression.
    2.   Logo bridging
    3.   Logo impressio
    4.   None of the above
17. Coated tablets showing micro- or macroscopic cracks across the surface, the defect is called,
    
    
    1.   Mottling
    2.   Orange peel effect
    3.   Film cracking
    4.   Twinning
18. Film cracking can be corrected by
    1.   Improving drying process
    2.   Increasing spray rate
    3.   Reducing the content of highly hygroscopic materials like MCC
    4.   All of the above
19. The tablet defect in the image is called as
    
    1.   Double impression
    2.   Doubling
    3.   Chipping
    4.   Chipping
20. Double impression can be corrected by
    1.   Using a non-rotating cam track
    2.   Decreasing speed of machine
    3.   Increasing speed of machine
    4.   Changing die