The Drugs used in treatment of Angina pectoris are called as antianginal drugs. Classification: Nitrates : a) Short acting (10 minutes): Glyceryl tri nitrate. (Nitroglycerine, GTN) b) Long Acting (1 hour): Isosorbide di nitrate, Isosorbide mono nitrate. 2. Calcium channel blockers: a) Phenyl alkyl amine: Verapamil. b) Benzothiazepin: Diltiazem. c) Dihydropyridines: Nifedipine, Amlodipine, Nimodipine, felodipine. 3. Beta Adrenergic Blockers: Propranolol, Atenolol, Metoprolol, Alprenolol. 4. Potassium Channel Openers: Nicorandil. 5. Miscellaneous: Dipyridamole, Trimetazidine, Ranolazine, Oxyphedrine etc. Nitrates 1) Glyceryl Tri Nitrate: It is heavy colorless explosive liquid. It as an organic nitrate compound and is synthesized by nitration of glycerin. Nitroglycerine was first used in treatment of angina pectoris by William Murrell in 1878. IUPAC Name: 1,3-dinitrooxypropan-2-yl nitrate. Mechanism of Action: Ni
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