Simple Pharmanotes

Amoebiasis also called as Amoebic dysentery is an intestinal infection caused due to a protozoa called as “ Entamoeba histolytica ” and is characterized by dysentery associated with presence of blood and mucus in feces. This can be chronic or acute with patients showing varying degree of illness from no symptoms to mild dysentery to severe dysentery causing collapse and even death of the patient. Diagnosis is can be done by stool testing for presence of Entamoeba histolytica. Treatment is aimed not only for the patients with symptoms but also for the one those who are dormant carriers of the disease. The drugs which are used in treatment of the Amoebiasis are called as “Antiamoebic Drugs” Life cycle of Entamoeba histolytica: Entamoeba histolytica exist in two life forms, Cysts: (Tough form, non-motile and can exist outside the body). Trophozoites: (Motile form, can not exist outside the body). Life cycle consists of following steps: Entry of cysts in the bod...

Leprosy is an infectious disease caused by a acid fast bacillus called as “ Mycobacterium leprae ”. Leprosy is called as “ Kushtharog or Maharog” in India. This disease is present from ancient times but,the Gregor Hansen in 1873 discovered the causative organism as “Mycobacterium leprae” hence the disease is called as “ Hansen’s Disease ” also. The leprosy bacillus attacks the schwan cell nucleus in neuron and hence affects the peripheral nervous system and skin.      Signs of Leprosy: Leprosy is characterized by presence of patches on skin, the patches of leprosy are characterized  by, Definite loss of sensation. Do not itch or hurt. hypopigmentation to reddish or copper red colored. No sensation of pain. May be flat or elevated. Diagnosis of Leprosy: Leprosy patches can easily be identified by checking sensation in comparison to normal skin. Skin smear test for presence of bacterias. Mycobacterium leprae: Its a acid fast bacil...