Simple Pharmanotes

    Joints in Human Body (Short). Introduction: A joint is the place in the body where bones of the skeleton meet. It is also called “Articulation.” Joints allow locomotion. Classification of Joints: Joints can be classified as structurally or functionally.  The structural classification of joints depends on the manner in which the bones connect to each other.  The functional classification of joints depends on the nature of the movement the joints allow. Arthrology is the branch of science that deals with the study of joints it is also called “Synosteology”. Structural Classification of Joints: The structural classification of joints is based on the type of tissue that binds the bones to each other at the joint.  There are three types of joints in the structural classification. Fibrous, Cartilaginous, Synovial joints. Fibrous Joints: These are joints in which bones are joined by dense connective tissue that is rich in collagen fibers.  These joints are als...

  Important Questions for First Sessional Examination . Long Questions: Explain the significance of controlled release systems and their design. Explain the physiological and biochemical features of Controlled Drug Delivery Systems . Answer :: Definition : Controlled drug delivery is one which delivers the drug at a predetermined rate, locally or systemically, for a specified period of time. However it is observed that many terms are used synonymously, to differentiate them from one another we are going to discuss different terminologies that are used in NDDS related to controlled release formulations. Rationale : To provide a location-specific action within the GIT. To avoid an undesirable local action within the GIT. To provide a programmed drug delivery pattern. To increase the rate and extent of absorption/bioavailability. To extend the duration of action of the drug. Significance : Maintains the drug level within the desired range. Useful for delivery of "difficult"’ dru...